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Menu
Home PageAll MoleculesRNF43
RNF43
RNF43 Overview
| English Name | E3 ubiquitin-protein ligase RNF43 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 | Target Synonym | |
| Highest Development Stage | Phase 1 Clinical | ||
| English Name | E3 ubiquitin-protein ligase RNF43 |
| Target Synonym | |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 |
| Highest Development Stage | Phase 1 Clinical |
RNF43 Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Human (1)
- Tag
Fc Tag (1)
- Conjugate
Unconjugated (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
RN3-H5256 |  Human | HEK293 | Human RNF43 Protein, Fc Tag (MALS verified) |  |  |  |
Total: 1
- 1
RNF43 Background
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| SZN-043 | SZN-043; SWEETS-1 | Phase 1 Clinical | Surrozen Inc | Hepatitis, Alcoholic; Liver Cirrhosis | Details |
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