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Serpin F1

Serpin F1 Overview

English NamePigment epithelium-derived factorApproved Drugs0
Drugs in Clinical Trials2Target SynonymCell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Highest Development StagePhase 3 Clinical
English NamePigment epithelium-derived factor
Target SynonymCell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 3 Clinical

Serpin F1 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
SE1-H5221
Human
HEK293
Human Serpin F1 / PEDF Protein, His Tag
Total: 1
  • 1

Serpin F1 Background

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1 Synonyms

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
BRM-421BRM-421Phase 3 ClinicalBrim Biotechnology Co LtdDry Eye Syndromes; Keratoconjunctivitis Sicca; Xerophthalmia
Details
DVC1-0401DVC1-0401Phase 2 ClinicalId Pharma, Kyushu UniversityRetinitis Pigmentosa
Details
  • Overview
  • Product List
  • Clinical Drug Information
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