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Siglec-7

Siglec-7 Overview

English NameSialic acid-binding Ig-like lectin 7Approved Drugs0
Drugs in Clinical Trials0Target SynonymCDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
Highest Development StagePreclinical
English NameSialic acid-binding Ig-like lectin 7
Target SynonymCDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
Approved Drugs0
Drugs in Clinical Trials0
Highest Development StagePreclinical

Siglec-7 Product List

  • Product Category

    Protein (4)

  • Product Status

    Launched (4)

  • Species

    Human (4)

  • Tag

    His Tag (1)His Tag & Avi Tag (1)Fc Tag (2)

  • Conjugate

    Unconjugated (3)Biotin-labeled (1)

Siglec-7 Background

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Siglec-7 Synonyms

CDw328,D-siglec,A79 membrane protein,p75,Adhesion inhibitory receptor molecule 1,AIRM-1
  • Overview
  • Product List
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