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Menu
Home PageAll MoleculesSpeB
SpeB
SpeB Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Streptococcus pyogenes (1)
- Tag
Tag Free (1)
- Conjugate
Unconjugated (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
SPB-S5115 | Streptococcus pyogenes | E. coli | SpeB (40U/μl) |  Add to Cart |
Total: 1
- 1
SpeB Background
SpeB is derived from Streptococcus pyogenes. It is an important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. It also cleaves human IL1B precursor to form biologically active IL1B and can induce apoptosis in human monocytes and epithelial cells in vitro, reduces phagocytic activity in monocytic cells. Thus, it may play a role in bacterial colonization, invasion, and inhibition of wound healing.
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