Select Language
Free Registration

TGF-beta RII

TGF-beta RII Overview

English NameTransforming growth factor beta receptor 2Approved Drugs0
Drugs in Clinical Trials5Target SynonymNONHSAG034676，TGF-beta receptor type II，Transforming Growth Factor Beta Receptor 2，Transforming Growth Factor， Beta Receptor II Alpha，Transforming Growth Factor Beta Receptor Type IIC，Transforming growth factor-beta receptor type II，TbetaR-II，TGF-beta type II receptor，TGFBR2，Transforming Growth Factor， Beta Receptor II (70/80kDa)，Transforming Growth Factor Beta Receptor II，TGFR-2，Transforming Growth Factor， Beta Receptor II Epsilon，Transforming Growth Factor， Beta Receptor II Delta，Transforming Growth Factor， Beta Receptor II Gamma，EC 2.7.11，Transforming Growth Factor， Beta Receptor II Beta，TGF-Beta Receptor Type IIB，TGF-Beta Receptor Type-2，EC 2.7.11.30，TGFbeta-RII，TBR-Ii，LDS1B，LDS2B，TAAD2，TBRII，AAT3，FAA3，LDS2，RIIC，MFS2，Receptor， Transforming Growth Factor-beta Type II，EC:2.7.11.30
Highest Development StagePhase 2 Clinical
English NameTransforming growth factor beta receptor 2
Target SynonymNONHSAG034676，TGF-beta receptor type II，Transforming Growth Factor Beta Receptor 2，Transforming Growth Factor， Beta Receptor II Alpha，Transforming Growth Factor Beta Receptor Type IIC，Transforming growth factor-beta receptor type II，TbetaR-II，TGF-beta type II receptor，TGFBR2，Transforming Growth Factor， Beta Receptor II (70/80kDa)，Transforming Growth Factor Beta Receptor II，TGFR-2，Transforming Growth Factor， Beta Receptor II Epsilon，Transforming Growth Factor， Beta Receptor II Delta，Transforming Growth Factor， Beta Receptor II Gamma，EC 2.7.11，Transforming Growth Factor， Beta Receptor II Beta，TGF-Beta Receptor Type IIB，TGF-Beta Receptor Type-2，EC 2.7.11.30，TGFbeta-RII，TBR-Ii，LDS1B，LDS2B，TAAD2，TBRII，AAT3，FAA3，LDS2，RIIC，MFS2，Receptor， Transforming Growth Factor-beta Type II，EC:2.7.11.30
Approved Drugs0
Drugs in Clinical Trials5
Highest Development StagePhase 2 Clinical

TGF-beta RII Product List

  • Product Category

    Protein (6)

  • Product Status

    Launched (6)

  • Species

    Human (5)Mouse (1)

  • Tag

    Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)His Tag (1)Llama IgG Fc Tag (1)

  • Conjugate

    Unconjugated (3)Biotin-labeled (3)

Total: 6
  • 1

TGF-beta RII Background

TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFβR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-β1 / TGFB1 and TGF-β3 / TGFB3 with high affinity and TGF-β2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

TGF-beta RII Synonyms

TGFBR2,TGFR2,TbetaR-II,TGFβR2

Product Reviews

  • A***n2022-07-30
    0People Like
    Human TGF-beta RII / TGFBR2 Protein, His Tag (MALS verified)
    I ordered Acro’s human TGF-beta Receptor II for Octet kinetics binding assays for several assays. Delivery was extremely quick and customer service was very responsive to questions I had. I first used this TGF-beta RII in an Octet binding kinetics assay and received high quality results that were consistent with what I expected. I also used this product as a TGF-beta sink in cytotoxicity assays. I have been impressed by the quality of Acro’s products.
  • Overview
  • Product List