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TPBG

TPBG Overview

English NameTrophoblast glycoproteinApproved Drugs0
Drugs in Clinical Trials16Target SynonymTrophoblast glycoprotein,5T4 oncotrophoblast glycoprotein,5T4,TPBG,5T4 oncofetal antigen,M6P1,5T4 oncofetal trophoblast glycoprotein,Wnt-Activated Inhibitory Factor 1,WAIF1,5T4AG,5T4-AG
Highest Development StagePhase 2 Clinical
English NameTrophoblast glycoprotein
Target SynonymTrophoblast glycoprotein,5T4 oncotrophoblast glycoprotein,5T4,TPBG,5T4 oncofetal antigen,M6P1,5T4 oncofetal trophoblast glycoprotein,Wnt-Activated Inhibitory Factor 1,WAIF1,5T4AG,5T4-AG
Approved Drugs0
Drugs in Clinical Trials16
Highest Development StagePhase 2 Clinical

TPBG Synonyms

TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

Antibody Project Trading Platform

Project NameProject StageMolecule TypeMolecule SourceDisease AreaIndication
5T4 mAb - 01LeadMonoclonalHumanized MouseSolid TumorOvarian cancer,Lung cancer

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Naptumomab estafenatoxTTS-CD3; ABR-217620Phase 2 ClinicalActive Biotech AbBreast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Melanoma; Mesothelioma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms
Details
ALG.APV-527ALG.APV 527; ADC-1016; ATOR-1016; ALG.APV-527; ALG-APV-527Phase 2 ClinicalAlligator Bioscience Ab, Aptevo Therapeutics IncNeoplasms; Solid tumours
Details
JK-06JK-06Phase 2 ClinicalXinlitai (Chengdu) Biological Technology Co LtdNeoplasms; Solid tumours
Details
TUB-030TUB-030Phase 2 ClinicalTubulis GmbHCarcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
Details
ACR-246ACR246; ACR-246; ADC2154; ADC-2154Phase 2 ClinicalHangzhou Adcoris Biopharmacy Co LtdBreast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Esophageal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Uterine Cervical Neoplasms
Details
IBR-854IBR854; IBR-854Phase 2 ClinicalImbioray (Hangzhou) Biomedicine Co LtdCarcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Solid tumours
Details
SYD-1875SYD-1875Phase 1 ClinicalSynthon BvSolid tumours
Details
ASN-004ASN-004Phase 1 ClinicalAsana Biosciences LlcSolid tumours
Details
anti-5T4 CAR NK-cell therapy (Wuxi Peapole's Hospital/Hangzhou Yingbairui Biomedical Technology)Phase 1 ClinicalImbioray (Hangzhou) Biomedicine Co LtdSolid tumours
Details
Naptumomab estafenatox/DurvalumabNTX-352Phase 1 ClinicalNeotx Therapeutics LtdSolid tumours
Details
XB-010XB-010Phase 1 ClinicalExelixis IncBreast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Squamous Cell Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
Details
FTL-008.16FTL-008.16; FTL008.16Phase 1 ClinicalSound(Chengdu)Biopharmacauticals Co LtdSolid tumours
Details
CBA-1535CBA-1535Phase 1 ClinicalChiome Bioscience IncCarcinoma, Non-Small-Cell Lung; Mesothelioma; Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Triple Negative Breast Neoplasms
Details
Anti-5T4 CAR-raNK Cell TherapyPhase 1 ClinicalImbioray (Hangzhou) Biomedicine Co LtdSolid tumours
Details
Prostate cancer vaccine(inactivated viral)(University of Oxford)ClinicalUniversity Of OxfordProstatic Neoplasms
Details
68Ga-NOTA-H006ClinicalHuashan HospitalSolid tumours
Details
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