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TRBC1

TRBC1

TRBC1 Overview

Molecule Name
TRBC1
Synonyms
T cell receptor beta constant 1,TRBC1
Drug Development Progress
Drugs in Clinical Trials4
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
T cell receptor beta constant 1，TRBC1，V_segment Translation Product，BV05S1J2.2，TCRBC1，TCRB
Background
The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRBC1 is the constant region of T-cell receptor (TCR) beta chain. TRBC1 is presented on the surface of T cell and recognized peptide-major histocompatibility (MH) (pMH) that are displayed by antigen presenting cells (APC). TRBC1 is participate in an adaptive immune response and has been well-studied in T cell therapy.

TRBC1 Product List

Species
  • Human（2）
Tag
  • His Tag（1）
  • His Tag & Avi Tag（1）
Host
  • HEK293（2）
Conjugate
  • Biotin-labeled（1）
  • Unconjugated（1）
Grade
  • RUO（2）
Low Endotoxin
  • Yes（1）
  • No（1）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
TRBC1
TR1-H52H4
Human TRBC1 Protein, His Tag, low endotoxin (HPLC verified)
Human
HEK293
HPLCSDS-PAGE

$360.00

100ug
TRBC1
Avitag
TR1-H82E6
Biotinylated Human TRBC1 Protein, His,Avitag™
Human
HEK293
SDS-PAGE

$360.00

25ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Invikafusp AlfaSTAR0602; STAR-0602Phase 2 ClinicalMarengo Therapeutics Inc
Abdominal Neoplasms; Breast Neoplasms; Carcinoma; Epstein-Barr Virus Infections; Lung Neoplasms; Neoplasms; Papillomavirus Infections; Solid tumours; Triple Negative Breast Neoplasms; Urogenital Neoplasms; Vulvar Diseases; Vulvar Neoplasms
Details
TRBC1/2-Targeted CAR-T Cell Therapy (Second Affiliated Hospital School Of Zhejiang University School Of Medicine)Phase 1 ClinicalSecond Affiliated Hospital School Of Zhejiang University School Of Medicine
Lymphoma, T-Cell, Peripheral
Details
Anti-TRBC1 CAR-T cell therapy (Shanghai General Hospital)Phase 1 ClinicalShanghai General Hospital
Hematologic Neoplasms
Details
FT-819FT-8198; FT-819; FT 8198Phase 1 ClinicalMemorial Sloan Kettering Cancer Center
Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Myositis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Scleroderma, Systemic
Details
Customer Reviews
  • 1***82022-08-03
    Human TRBC1 Protein, His Tag, low endotoxin (HPLC verified)
    The TRBC1 protein is really helpful! Recently, our experiment has not been smooth UNTIL we used the TRBC1 protein and then things finally started to come together! It turns out we were not using the right protein which stopped us from continuing our project. Thank you so much!