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TSHR

TSHR Overview

English NameThyroid stimulating hormone receptorApproved Drugs3
Drugs in Clinical Trials6Target SynonymTSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
Highest Development StageApproved
English NameThyroid stimulating hormone receptor
Target SynonymTSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
Approved Drugs3
Drugs in Clinical Trials6
Highest Development StageApproved

TSHR Product List

  • Product Category

    Cell (3)Protein (1)

  • Product Status

    Launched (4)

  • Species

    Human (4)

  • Tag

    - (4)

  • Conjugate

    - (3)Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
CHEK-ATF187
Human
HEK293
Human TSHR (Luc) HEK293 Reporter Cell
CHEK-ATP086
Human
HEK293
HEK293/Human TSHR Stable Cell Line
SCCHO-ATP085
Human
CHO
CHO/Human TSHR Stable Cell Line
TSR-H52P3
Human
HEK293
Human TSHR Full Length Protein (VLP)
Total: 4
  • 1

TSHR Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

TSHR Synonyms

TSHR,TSH-R,LGR3,TSH R

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Anti-thyroid stimulating hormone receptor chimeric antigen receptor T cell therapy (Innovative Cellular Therapeutics)ICTCAT-023Phase 2 ClinicalInnovative Cellular Therapeutics Co LtdThyroid Neoplasms
Details
ZG-001(Zhigen)ZG-001(Zhigen); JH-001Phase 2 ClinicalHunan Warner Pharmaceutical Factory Chiral Medicine Co Ltd, Hunan Warrant Pharmaceutical Co Ltd, Shanghai Zhigen Pharmaceutical Technology Co LtdDepressive Disorder; Depressive Disorder, Major
Details
ICTCAR-051ICTCAR-051Phase 1 ClinicalInnovative Cellular Therapeutics Co LtdSolid tumours; Thyroid Neoplasms
Details
KSP-0914Phase 1 ClinicalKissei Pharmaceutical Co LtdGraves Disease
Details
GensSci098GenSci098; GenSci-098; GensSci-098; GensSci098; GS-098; YB-101Phase 1 ClinicalChangchun GeneScience Pharmaceuticals Co LtdGoiter; Graves Disease; Graves Ophthalmopathy
Details
ICTCAR-TCICTCAR-TCClinicalInnovative Cellular Therapeutics Co LtdThyroid Neoplasms
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
Thyrotropin alfarh-TSH; MRrhTSH; rhTSH-MApprovedGenzyme CorpThyrogenUnited StatesThyroid NeoplasmsGenzyme Corp1998-11-30Diagnostic agents; Goiter, Nodular; Thyroid Neoplasms
Details
Recombinant human thyrotropin (Zelgen Biosciences)ApprovedSuzhou Zelgen Biosciences Co Ltd赛诺璟, 泽速宁Mainland ChinaThyroid NeoplasmsSuzhou Zelgen Biopharmaceuticals Co Ltd2026-01-05Thyroid Neoplasms
Details
Recombinant human thyroid stimulating hormone(Smartnuclide)SNA-001; SNA001; KN040; KN-040ApprovedSmartnuclide Biopharma智舒嘉Mainland ChinaThyroid NeoplasmsSmartnuclide Biopharma2024-04-02Thyroid Neoplasms
Details
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