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UL18 & B2M

UL18 & B2M Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) & Human (1)

  • Tag

    His Tag & Avi Tag (1)

  • Conjugate

    Biotin-labeled (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
ULM-V82W3
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) & Human
HEK293
Biotinylated Human cytomegalovirus (strain AD169) (HHV-5) & Human UL18 & B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
Total: 1
  • 1

UL18 & B2M Background

Human cytomegalovirus (HCMV) encodes UL18, a viral MHC‑I homolog that mimics human HLA class I molecules. UL18 forms a stable heterodimer with human β2‑microglobulin (B2M), enabling proper folding and high‑affinity interaction with the inhibitory receptor LIR‑1/ILT2 on immune cells. This interaction suppresses NK‑cell activation and contributes to HCMV immune evasion. Recombinant UL18–B2M complexes are widely used to study viral immunomodulation and receptor–ligand interactions.
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