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Menu
Home PageAll MoleculesZNRF3
ZNRF3
ZNRF3 Overview
| English Name | E3 ubiquitin-protein ligase ZNRF3 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 | Target Synonym | |
| Highest Development Stage | Phase 1 Clinical | ||
| English Name | E3 ubiquitin-protein ligase ZNRF3 |
| Target Synonym | |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 1 |
| Highest Development Stage | Phase 1 Clinical |
ZNRF3 Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Human (1)
- Tag
His Tag (1)
- Conjugate
Unconjugated (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
ZN3-H52H3 |  Human | HEK293 | Human ZNRF3 protein, His Tag (MALS verified) |  |  |  |
Total: 1
- 1
ZNRF3 Background
The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| SZN-043 | SZN-043; SWEETS-1 | Phase 1 Clinical | Surrozen Inc | Hepatitis, Alcoholic; Liver Cirrhosis | Details |
- Overview
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