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Recombinant Monoclonal Anti-CD19 Antibody, Rabbit (4A6)

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HGS-S259-20ul
$125.00
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HGS-S259-100ul
$360.00
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HGS-S259
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Product Details
Performance Data
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  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Recombinant Monoclonal Anti-CD19 Antibody, Rabbit (4A6) is a CD19 primary antibody for IHC application.

Antibody Type

Recombinant Monoclonal

Clone

4A6

Isotype

Rabbit IgG, Rabbit Kappa

Host Species

Rabbit

Reactivity

Human

Specificity

React with CD19 protein on the membrane of target cell/tissue.

Application
Application
Recommended Use
IHC-P
1: 500 - 1: 2000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

0.9~1.1 mg/ml

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS containing BSA, with Glycerol as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • 2°C to 8°C for 14 days;
  • -20°C to -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD19 functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. It decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens, and activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. CD19 is not required for early steps during B cell differentiation in the blood marrow but required for normal differentiation of B-1 cells (By similarity), normal B cell differentiation and proliferation in response to antigen challenges, normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.