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PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (0.03% Proclin)

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FABm065-01-200tests (50tests X 4)
$200.00
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FABm065-01
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Product Details
Performance Data
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  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

Clone

AS672

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Immunogen

Purified Human CD43 Protein

Conjugate

PE

Excitation Wavelength: 488 nm / 561 nm

Emission Wavelength: 575 nm

Specificity

This product is a specific antibody specifically reacts with CD43 protein.

Application

Flow Cytometry (Evaluation of the expression of CD43 on Human cells).

Recommended Dilution

1:20

Isotype Control

The isotype control is sold separately; please refer to Cat. No. DNP-PM1 for product information.

Form

Liquid

Formulation

Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD43, also designated Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein and W3/13, is a large type I transmembrane glycoprotein enriched with O-glycosylation and sialylation sites. It binds to CD54 (ICAM-1), CD62E, CD169 (Siglec-1), CD328 (Siglec-7) and MHC Class I molecules. Widely expressed on T lymphocytes, thymocytes, monocytes, granulocytes, bone marrow stem cells, pre-B cells, activated B cells and plasma cells—but absent on resting peripheral blood B cells, red blood cells and nonhematopoietic cells—CD43 modulates leukocyte functions (bidirectional adhesion, T cell costimulation, apoptosis induction) via intercellular interactions. Enzymatic shedding of activated leukocyte surface CD43 may exert negative regulation on adaptive immune responses, making it a valuable target for flow cytometry analysis.