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Recombinant Monoclonal Anti-CD45(LCA) Antibody, Rabbit (1C3)

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HGS-S261-100ul
$470.00
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Product Details
Performance Data
Reviews & Citations
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  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Recombinant Monoclonal Anti-CD45(LCA) Antibody, Rabbit (1C3) is a CD45(LCA) primary antibody for IHC application.

Antibody Type

Recombinant Monoclonal

Clone

1C3

Isotype

Rabbit IgG, Rabbit Kappa

Host Species

Rabbit

Reactivity

Human

Specificity

React with CD45(LCA) protein on the membrane of target cell/tissue.

Application
Application
Recommended Use
IHC-P
1: 500 - 1: 2000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

0.9~1.1 mg/ml

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS containing BSA, with Glycerol as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • 2°C to 8°C for 14 days;
  • -20°C to -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD45(LCA) acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).