Biotinylated Monoclonal Anti-Datopotamab Antibody, Mouse IgG1 (7D3)

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Cat. No. / Size
Price
Qty
DAB-BLY2439a-25ug
$360.00
DAB-BLY2439a-200ug
$1565.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Biotinylated Monoclonal Anti-Datopotamab Antibody, Mouse IgG1 (7D3) is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    7D3

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Conjugate

    Biotin

  • Specificity

    Specifically recognizes Human Datopotamab; This antibody is a neutralizing antibody.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Datopotamab ELISA

    Immobilized Monoclonal Anti-Datopotamab Antibody, Mouse IgG1 (5D6) (Cat. No. DAB-MY2438a) at 1 μg/mL, add Datopotamab and then add Biotinylated Monoclonal Anti-Datopotamab Antibody, Mouse IgG1 (7D3) (Cat. No. DAB-BLY2439a) at 2 μg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).

    Protocol

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Background

A humanized monoclonal IgG1 antibody that binds to human trophoblast cell surface antigen 2 (TROP2), a transmembrane glycoprotein overexpressed on the surface of various epithelial tumor cells. Datopotamab contains human constant regions and variable regions (complementarity-determining regions) derived from a murine antibody specific for TROP2. It is produced in a Chinese Hamster Ovary (CHO) mammalian cell expression system and has a molecular weight of approximately 148 kilodaltons.

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