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COADS MSDS

Recombinant Monoclonal Anti-ICAM-1 Antibody, Rabbit (C056)

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COADS MSDS
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HGS-M2739-20ul
$110.00
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HGS-M2739-100ul
$305.00
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HGS-M2739
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Recombinant Monoclonal Anti-ICAM-1 Antibody, Rabbit (C056) is an ICAM-1 primary antibody for IHC application.

Antibody Type

Recombinant Monoclonal

Clone

C056

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit

Reactivity

Human

Specificity

React with ICAM-1 protein on the membrane of target cell/tissue.

Application
Application
Recommended Use
IHC-P
1: 100 - 1: 500

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

0.9~1.1 mg/ml

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS containing 40% Glycerol, 0.03% Proclin 300 and 0.05% BSA, with Trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • 2°C to 8°C for 14 days;
  • -20°C to -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

ICAM-1 (CD54) is a 90 kDa immunoglobulin superfamily adhesion molecule with low basal expression that is strongly induced by inflammatory cytokines (TNF-α, IFN-γ, IL-1) via the NF-κB/JAK-STAT pathways. It mediates immune cell adhesion and transendothelial migration by binding to LFA-1/Mac-1 on leukocytes, and also participates in T-cell immunological synapse formation. In tumors such as TNBC, HCC, and gastric cancer, high ICAM-1 expression on tumor cells promotes invasion and metastasis, correlating with poor prognosis.