Recombinant Monoclonal Anti-MSH6 Antibody, Rabbit (4C7)

Product Details

Background
Recombinant Monoclonal Anti-MSH6 Antibody, Rabbit (4C7) is a MSH6 primary antibody for IHC application. MSH6 leads mismatch repair (MMR), which is a DNA repair pathway that corrects mispaired based in DNA molecules and restore the correct nucleotide sequence. MSH6 is over-expressed in a variety of tumors in the colon, ovary and stomach.

Host Species	Rabbit
Isotype	Rabbit IgG, Rabbit Kappa
Clone	4C7
Application	IHC-P
Dilution Ratio	1: 200 - 1: 1000
Form	Liquid
Clonality	Monoclonal
Reactivity	Human
Synonyms	MSH6
Concentration	0.9~1.1 mg/ml
Specificity	React with MSH6 protein on the intracellular area of target cells
Purification Tech	Protein A
Preservation	PBS, BSA, Glycerol

Experiment Protocol
LEICA Experiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.
ACRO Quality Management System

Sample Staining Data
Immunohistochemical analysis of paraffin embedded human colorectal cancer tissue labelled with HGS-S313 at 1:500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human gastric cancer tissue labelled with HGS-S313 at 1:500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human thyroid cancer tissue labelled with HGS-S313 at 1:500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Drug Candidate Licensing