Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3)

Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3) is a PD-1 primary antibody for IHC application. Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.

Recombinant Monoclonal

2F3

Mouse IgG

Mouse

Human

React with PD-1 protein on the membrane of target cell/tissue

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Protein A purified.

0.9~1.1 mg/ml

Liquid

Supplied a 0.22 μm-filtered solution in Tris buffer, 1% BSA.

Please contact us for customized product forms or formulations.

Liquid product is shipped at blue ice.

Please avoid repeated freeze-thaw cycles.

• 2°C to 8°C for 14 days;
• -20°C to -70°C for 12 months.

Product Specific Notices: For research use only.