Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6)

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Cat. No. / Size
Price
Qty
PEG-M731-100ug
$355.00
PEG-M731-500ug
$1725.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6) is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    5G3-1C6

  • Isotype

    Human IgG1, Kappa

  • Immunogen

    PEG

  • Specificity

    Specifically recognizes PEG.

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified / Protein G purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 3.0) containing HAC, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     PEG ELISA

    Immobilized BSA-PEG-1-2-40528 at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6) (Cat. No. PEG-M731) with a linear range of 0.002-0.156 μg/mL (QC tested).

    Protocol

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Background

Polyethylene glycol (PEG) is a synthetic polymer widely used in pharmaceuticals as a stabilizer and excipient. PEGylation—the attachment of PEG chains to proteins or drugs—improves solubility, prolongs circulation half life, and reduces immunogenicity. Several PEGylated therapeutics, such as PEG interferon and PEG filgrastim, are already in clinical use. However, anti PEG antibodies may affect drug efficacy, making reliable detection tools essential for research and quality control.

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