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Product Details
Background
Recombinant Monoclonal Anti-PTK7 Antibody, Rabbit (P2A01) is a PTK7 primary antibody for IHC application.
PTK7 is a member of the receptor tyrosine kinase (RTK) superfamily, plays a critical role in regulating cell polarity, migration and tissue homerostasis during vertebrate development. PTK7 can form heterdimers and function as a signal enhancer or co-receptor, deeply involved in the switching of WNT signaling pathway. PTK7 is overexpressed in a variety of tumors, such as cervical cancer, colorectal cancer, breast cancer and so on, where it is closely associated with tumorigenesis and progression.Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaCloneP2A01ApplicationIHC-PDilution Ratio1: 100 - 1: 500FormLiquidClonalityMonoclonalReactivityHumanSynonymsCCK4Concentration0.9~1.1 mg/mlSpecificityReact with PTK7 protein on the membrane of target cell/tissuePurification TechFc-TagPreservationPBS, 11% Trehalose, 40% Glycerol, 0.03% Proclin 300, 0.05% BSAExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Performance Data
Sample Staining Data
Immunohistochemical analysis of paraffin embedded human cervical cancer labelled with HGS-M2715 at 1/200 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human uterus tissue labelled with HGS-M2715 at 1/200 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
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Drug Development Progress- English Name：
Protein-tyrosine kinase 7
- Category：
- Approved Drugs：
0 Details
- Drugs in Clinical Trials：
8 Details
- Highest Development Stage：
Phase 2 Clinical
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