Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Trehalose free)

Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed in HEK293 cells, which combines the variable regions of a mouse monoclonal antibody with human IgG1 constant domains. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2).

Recombinant Monoclonal

AM122

Human IgG1, Kappa

Mouse

Virus

This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Protein A purified.

Less than 10%, as determined by SEC-MALS.

Please refer to the Certificate of Analysis (CoA).

Liquid

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4).

Please contact us for customized product forms or formulations.

Please avoid repeated freeze-thaw cycles.

• For long term storage, the product is stable for up to 3 years at -70°C from date of receipt;
• For short term storage, the product is stable for up to 12 months at 2-8°C from date of receipt.

Product Specific Notices: For research use only.