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Anti-SARS-CoV-2 Spike S2 Antibody, Human IgG4 (AS86)

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S2N-S86-100ug
$450.00
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S2N-S86-1mg
$3,255.00
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S2N-S86
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Product Details
Performance Data
Reviews & Citations
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

  • Source

    Anti-SARS-CoV-2 Spike S2 Antibody, Human IgG4 (AS86) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from CHO cells.

  • Clone

    AS86

  • Isotype

    Human IgG4 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Specificity

    This product is a specific antibody against SARS-CoV-2 Spike S2 protein. Cross-reactivity with S2 protein of other coronaviruses has not been tested.

  • Application

    Application
    Recommended Usage
    ELISA
    0.13-30 ng/mL

  • Purity

    95% as determined by SDS-PAGE.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH6.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.