ActiveMax® DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm)

Product Description

ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) are uniform, superparamagnetic beads of 5.5 µm coated with an optimized mixture of human VCAM-1/CD106 protein (premium grade) and human DLL4 protein (premium grade). They were expressed from human 293 cells (HEK293). Human VCAM-1 / CD106 protein contains AA Phe 25 - Glu 698 (Accession # P19320-1), and human DLL4 protein contains AA Ser 27 - Pro 524 ((Accession # NP_061947.1).
ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

Application

ActiveMax® Human DLL4/VCAM-1 μBeads, premium grade (for cells, 5.5 μm) is designed to synergistically activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs). The synergistic interactions between Notch ligand Delta-like 4 and VCAM-1 are leveraged to enhance Notch signaling to support efficient T-cell lineage commitment, so the beads are recommended to use for in vitro production of induced pluripotent stem cell derived T cells.

Reconstitution

See Certificate of Analysis (CoA) for detailed instruction.

Storage

This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

Please protect from light and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended.

Sterility

Negative

Endotoxin

Less than 0.002 EU per μg by the LAL method / rFC method.

Mycoplasma

Negative

Important Note

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

Formulation

Lyophilized in PBS with 0.1% HSA, pH 7.4. Trehalose is added as a protectant before lyophilization.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process