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Human CCL17 / TARC Protein, Fc Tag (MALS verified)

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CC7-H5256-20ug
$185.00
In Stock - Delivery in 1-2 business days
CC7-H5256-50ug
$370.00
In Stock - Delivery in 1-2 business days
CC7-H5256-1mg
$3,400.00
In Stock - Delivery in 1-2 business days
CC7-H5256
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

TARC, ABCD-2, SCYA17, A-152E5.3

Source

Human CCL17, Fc Tag (CC7-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 94 (Accession # Q92583-1).

Predicted N-terminus: Ala 24

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 34.5 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100mM Gly, 25mM Arginine, 150mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

CCL17, a chemokine ligand for CCR4, predominantly secreted by dendritic cells and endothelial cells. It drives Th2 cell migration in allergic inflammation, atopic dermatitis, and asthma. Elevated serum CCL17 serves as a sensitive biomarker for disease activity in Hodgkin lymphoma and atopic diseases.