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Human CCL3 / MIP-1 alpha Protein, His Tag

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CC3-H5249-20ug
$185.00
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CC3-H5249-50ug
$370.00
In Stock - Delivery in 1-2 business days
CC3-H5249-1mg (500ug X 2)
$3,090.00
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CC3-H5249
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

C-C motif chemokine 3, MIP1-(a), AI323804, CCL3, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, MIP1A, MIP-1alpha, MIP1-alpha

Source

Human CCL3, His Tag (CC3-H5249) is expressed from E. coli cells. It contains AA Ser 24 - Ala 92 (Accession # P10147-1).

Predicted N-terminus: Met

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 9.7 kDa. The protein migrates as 12-13 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 20 mM Tris,150 mM NaCl,0.2 M Arginine,pH8.0 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).