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Cynomolgus CD109 / CPAMD7 Protein, His Tag

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Cat. No. / Size
Price
Qty
CD9-C52H5-100ug
$270.00
CD9-C52H5-1mg (500ug X 2)
$1475.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Synonyms

    CD109, CPAMD7, r150, p180, CPAMD7

  • Source

    Cynomolgus CD109 Protein, His Tag (CD9-C52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Ser 1266 (Accession # A0A2K5VNN2).

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  • Molecular Characterization

    CD109 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 141.7 kDa. The protein migrates as 160-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CD109 SDS-PAGE

    Cynomolgus CD109 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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Background

CD109 is a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. CD109 is expressed in many malignant tumors, including various squamous cell carcinomas and adenocarcinomas, and plays a role as a multifunctional coreceptor.CD109 reportedly associates with transforming growth factor (TGF)-β receptors and negatively regulates TGF-β signaling in keratinocytes. Additionally, CD109 is potentially related to signal transducer and activator of transcription-3 signaling and aberrant cell proliferation.

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Drug Development Progress
  • English Name:

    DNA polymerase alpha subunit

  • Category:

  • Approved Drugs:

    2 Details

  • Drugs in Clinical Trials:

    3 Details

  • Highest Development Stage:

    Approved

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