Biotinylated Human CD84 / SLAMF5 Protein, His,Avitag™

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Cat. No. / Size
Price
Qty
CD4-H82E5-25ug
$360.00
CD4-H82E5-200ug
$1565.00
ETA of in-stock products:2 business days

Product Details

  • Synonym

    CD84, SLAMF5, LY9B, SLAMF5

  • Source

    Biotinylated Human CD84, His,Avitag (CD4-H82E5) is expressed from human 293 cells (HEK293). It contains AA Lys 22 - Gly 225 (Accession # Q9UIB8-3).

    Predicted N-terminus: Lys 22

    Request for sequence
  • Molecular Characterization

    CD84 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 26.5 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CD84 SDS-PAGE

    Biotinylated Human CD84, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

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Background

Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.

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