Human FAM3C Protein, His Tag (MALS verified)

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Cat. No. / Size
Price
Qty
FAC-H52H3-100ug
$350.00
FAC-H52H3-1mg
$1980.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    GS3786, ILEI

  • Source

    Human FAM3C Protein, His Tag (FAC-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 227 (Accession # Q92520).

    Predicted N-terminus: Gln 25

    Request for sequence
  • Molecular Characterization

    FAM3C Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 24 kDa. The protein migrates as 25-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    FAM3C SDS-PAGE

    Human FAM3C Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    FAM3C SEC-MALS

    The purity of Human FAM3C Protein, His Tag (Cat. No. FAC-H52H3) is more than 90% and the molecular weight of this protein is around 20-32 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     FAM3C ELISA

    Immobilized Human FAM3C Protein, His Tag (Cat. No. FAC-H52H3) at 1 μg/mL (100 μL/well) can bind various dilution ratio of Anti-FAM3C Antibody, Rabbit Polyclonal (QC tested).

    Protocol

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Background

FAM3C, is a member of the Family with Sequence Similarity 3 (FAM3) cytokine family, also called Interleukine-like EMT inducer (ILEI). FAM3C is widely expressed in the human secretory epithelia and participates in numerous biological processes, including hepatic glucose and lipid metabolism , osteogenic differentiation , retinal laminar formation and brain amyloid-β (Aβ) peptide production. It has been described as an important cytokine for invasion, epithelial‐mesenchymal transition (EMT), and cancer metastasis.

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