Human FASN Protein, His Tag (active enzyme)

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FAN-H5143-100ug
$350.00
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FAN-H5143-1mg
$2,310.00
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FAN-H5143
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Synonyms

FAS, OA-519, SDR27X1

Source

Human FASN Protein, His Tag (FAN-H5143) is expressed from E. coli cells. It contains AA Leu 2200 - Gly 2511 (Accession # NP_004095-1).

Predicted N-terminus: Met

Molecular Characterization

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 58.3 kDa. The protein migrates as 34-39 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity

>95% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 20 mM Tris, 500 mM NaCl, pH7.9 with glycerol as protectant.

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Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

Background

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]