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Product Details
Synonyms
IL-11 R alpha, IL-11 RA, IL11RA, Interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha
Source
Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag (ILR-R82E3) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Gln 365 (Accession # F7H9Z9).
Predicted N-terminus: Ser 23
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 41.1 kDa. The protein migrates as 41-46 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Conjugate
Biotin-labeled
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag (Cat. No. ILR-R82E3) is more than 90% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Cynomolgus IL-11 Protein, His Tag (Cat. No. IL1-C5243) at 5 μg/mL (100 μL/well) can bind Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag (Cat. No. ILR-R82E3) with a linear range of 0.2-20 ng/mL (QC tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Interleukin 11 receptor alpha
- Category：
- Approved Drugs：
9 Details
- Drugs in Clinical Trials：
3 Details
- Highest Development Stage：
Approved
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