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Product Details
Synonyms
IL-31 RA, IL-31RA, hGLM-R, CRL3, GPL, ZcytoR17, GLM-R, IL-31R-alpha, Gp130-like receptor
Source
Cynomolgus IL-31 RA Protein, Fc Tag (ILA-H525b) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # XP_005556977.2).
Predicted N-terminus: Ala 20
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 83.5 kDa. The protein migrates as 110-140 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Cynomolgus IL-31 RA Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-ELISA
Immobilized Cynomolgus IL-31, His Tag (Cat. No. IL1-C5245) at 1 μg/mL (100 μL/well) can bind Cynomolgus IL-31 RA Protein, Fc Tag (Cat. No. ILA-H525b) with a linear range of 2-78 ng/mL (QC tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Interleukin-31 receptor subunit alpha
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
0 Details
- Highest Development Stage：
Approved
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