COA
- Product Details
- Performance Data
- Reviews & Citations
- Resources
1/3
No data
Human ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free AIDD-Ready protein is designed for direct use in SPR assays. It is supplied in a sugar-free, glycerol-free formulation to eliminate refractive index interference in SPR. No desalting or buffer exchange is required before use, simplifying the SPR workflow and supporting high-throughput experimental validation to accelerate the transition from AI prediction to wet-lab validation.
Integrin alpha V beta 6, ITGAV&ITGB6
Human ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free (IT6-H52E1AI) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gly 22 - Asn 707 (ITGB6) (Accession # NP_002201.1 (ITGAV) & AAI21179.1 (ITGB6)).
Predicted N-terminus: Phe 31 & Gly 22
Human ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB6, has a calculated MW of 112.9 kDa (ITGAV) & 79.6 kDa (ITGB6). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and an Avi tag (Avitag™) and subunit ITGB6 contains no tag but a basic tail at the C-terminus. The protein migrates as 90-110 kDa, 120-125 kDa and 130-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
The protein is designed as a heterodimer.
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulated in a proprietary trehalose-free buffer, supplied ready-to-use for SPR/BLI analysis - no buffer exchange required.
For detailed formulation, please refer to the batch-specific COA.
This product is supplied and shipped on dry ice.
Please avoid repeated freeze-thaw cycles.