My Cart

Human Nr4a1 Protein, His Tag (MALS verified)

Customer Reviews
Cat. No. / Size
Price
Qty
NR1-H5144-100ug
$410.00
NR1-H5144-1mg (200ug X 5)
$2885.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Synonyms

    Nuclear receptor subfamily 4 group A member 1

  • Source

    Human Nr4a1 Protein, His Tag (NR1-H5144) is expressed from E. coli cells. It contains AA Ser 351 - Phe 598 (Accession # P22736-1).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    Nr4a1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 29.5 kDa. The protein migrates as 25 kDa and 29-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • SDS-PAGE

    Nr4a1 SDS-PAGE

    Human Nr4a1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Nr4a1 SEC-MALS

    The purity of Human Nr4a1 Protein, His Tag (Cat. No. NR1-H5144) is more than 90% and the molecular weight of this protein is around 32-42 kDa verified by SEC-MALS.

    Report

Customer Reviews
Writing Reviews

Background

Orphan nuclear receptor 4A1(NR4A1) belongs to the NR4A superfamily and plays an important role in inflammation, cell metabolism, proliferation and differentiation. NR4A1 expression can be induced by various stimuli in macrophages. NR4A1 has a bidirectional effect of inhibiting or promoting the inflammatory response of atherosclerosis (AS), which may be related to the different microenvironment, cell phenotype and transfection vector. NR4A1 can promote pathological angiogenesis, which is an important factor affecting plaque instability. The role of NR4A1 in inflammation and pathological angiogenesis of AS was reviewed, in order to provide a target for the treatment of stable plaque and provide a reference for the prevention and treatment of AS.

Recent Advances

 
Contact Us
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background
Contact Us

[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521

[North America]: 1 Innovation Way, Newark, DE 19711, USA
[Switzerland]: ACRObiosystems AG, c/o Zug Dammstrasse Centre AG, Dammstrasse 19, 6300 Zug Switzerland