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Product Details
Synonyms
TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Source
Cynomolgus / Rhesus macaque OX40, Fc Tag (OX0-C5251) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Ala 214 (Accession # XP_001090870.1). In the region Lys 28 - Ala 214, the amino acid sequences of Cynomolgus and Rhesus macaque OX40 are identical.
Predicted N-terminus: Lys 28
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Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 46.9 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Cynomolgus / Rhesus macaque OX40, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Cynomolgus / Rhesus macaque OX40, Fc Tag (Cat. No. OX0-C5251) is more than 85% and the molecular weight of this protein is around 115-140 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Human OX40 Ligand, His Tag (active trimer) (Cat. No. OXL-H52Q8) at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque OX40, Fc Tag (Cat. No. OX0-C5251) with a linear range of 0.2-3 ng/mL (QC tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Tumor necrosis factor receptor superfamily member 4
- Category：
- Approved Drugs：
0 Details
- Drugs in Clinical Trials：
29 Details
- Highest Development Stage：
Phase 3 Clinical
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