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Human PADI6 Protein, His Tag

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PA6-H5545-50ug
$620.00
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PA6-H5545-1mg
$4,325.00
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PA6-H5545
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Product Details
Performance Data
Reviews & Citations
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

  • Synonyms

    PADI6, PREMBL2, Peptidylarginine Deiminase VI, Peptidylarginine Deiminase Type 6

  • Source

    Human PADI6 Protein, His Tag (PA6-H5545) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 694 (Accession # Q6TGC4).

    Predicted N-terminus: Met

    Request for sequence

  • Molecular Characterization

    PADI6 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 79.7 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50mM Tris, 150mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Background

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.