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Product Details
Synonym
Papain-like Protease, Replicase polyprotein 1a, ORF1a polyprotein, pp1a, 1a, PL-PRO, Plpro
Source
SARS-CoV-2 Papain-like Protease, His Tag (PAE-C5148) is expressed from E. coli cells. It contains AA Glu 746 - Lys 1060 (Accession # YP_009725299.1).
Predicted N-terminus: Met
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 37.6 kDa. The protein migrates as 35-37 kDa under reducing (R) condition (SDS-PAGE).
Purity
>95% as determined by SDS-PAGE.
Formulation
Supplied as 0.2 μm filtered solution in 50 mM HEPES, 300 mM NaCl, pH7.5, 11% Trehalose with glycerol as protectant.
Contact us for customized product form or formulation.
Shipping
This product is supplied and shipped with dry ice, please inquire the shipping cost.
Storage
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
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Performance Data
SDS-PAGE
SARS-CoV-2 Papain-like Protease, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity
Measured by its ability to convert the substrate Dabcyl–FRLKGGAPIKGV–Edans.The specific activity is >2500 pmol/min/mg (QC tested).
Protocol
Customer Reviews Writing Reviews
Background
Recent Advances
Drug Development Progress- English Name：
SARS-CoV-2-3C-like-proteinase
- Category：
- Approved Drugs：
5 Details
- Drugs in Clinical Trials：
29 Details
- Highest Development Stage：
Approved
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