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Biotinylated Mouse Transferrin R / CD71 Protein, Avitag™,His Tag (MALS verified)

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Cat. No. / Size
Price
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TFR-M82E3-25ug
$415.00
TFR-M82E3-200ug
$1880.00
ETA of in-stock products:2 business days
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Product Details

  • Synonyms

    CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

  • Source

    Biotinylated Mouse Transferrin R Protein, Avitag,His Tag (TFR-M82E3) is expressed from human 293 cells (HEK293). It contains AA Cys 89 - Phe 763 (Accession # Q62351-1).

    Predicted N-terminus: Gly

    Request for sequence
  • Molecular Characterization

    Transferrin R Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a polyhistidine tag.

    The protein has a calculated MW of 79.5 kDa. The protein migrates as 85-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a dimer.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Transferrin R SDS-PAGE

    Biotinylated Mouse Transferrin R Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Transferrin R SEC-MALS

    The purity of Biotinylated Mouse Transferrin R Protein, Avitag,His Tag (Cat. No. TFR-M82E3) is more than 95% and the molecular weight of this protein is around 145-180 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Transferrin R ELISA

    Immobilized Biotinylated Mouse Transferrin R Protein, His,Avitag (Cat. No. TFR-M82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse Transferrin Protein, Mouse IgG2a Fc Tag (Cat. No. TRN-M525b) with a linear range of 0.2-6 ng/mL (QC tested).

    Protocol
  •  Transferrin R ELISA

    Immobilized Human Transferrin Protein, His Tag (Cat. No. TRN-H52H3) at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse Transferrin R Protein, His,Avitag (Cat. No. TFR-M82E3) with a linear range of 0.1-16 ng/mL (Routinely tested).

    Protocol

Customer Reviews
Writing Reviews

  • S*** 2025-11-18
    Likes
    Used this material as a captured ligand in routine SPR testing on a Biacore. Material is clean, consistent, and easy to work with, and can be used to generate quality data

Background

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Recent Advances

 
Drug Development Progress
  • English Name:

    Transferrin receptor protein 1

  • Category:

  • Approved Drugs:

    1 Details

  • Drugs in Clinical Trials:

    15 Details

  • Highest Development Stage:

    Approved

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