Human UBE1 / UBA1 Protein, His Tag (MALS verified)

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Cat. No. / Size
Price
Qty
UB1-H5248-25ug
$115.00
UB1-H5248-100ug
$350.00
UB1-H5248-500ug
$1450.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    A1S9T and BN75 temperature sensitivity complementing, A1S9T, A1ST, AMCX1, GXP1, MGC4781, POC20 centriolar protein homolog, POC20, Protein A1S9, SMAX2, UBA1, UBA1, ubiquitin-activating enzyme E1 homolog A, UBA1A, UBE1, UBE1A1S9, UBE1X, ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivitycomplementing), Ubiquitin-activating enzyme E1, Ubiquitinactivating Enzyme, Ubiquitin-activating Enzyme, ubiquitin-like modifier activating enzyme 1, ubiquitin-like modifier-activating enzyme 1

  • Source

    Human UBE1/UBA1, His Tag (UB1-H5248) is expressed from Baculovirus-Insect cells. It contains AA Ser 2- Arg 1058 (Accession # P22314-1).

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  • Molecular Characterization

    UBE1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 119.8 kDa. The protein migrates as 120-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    UBE1 SDS-PAGE

    Human UBE1/UBA1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    UBE1 SEC-MALS

    The purity of Human UBE1/UBA1, His Tag (Cat. No. UB1-H5248) is more than 85% and the molecular weight of this protein is around 115-135 kDa verified by SEC-MALS.

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Background

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

Recent Advances

 
Drug Development Progress
  • English Name:

    Ubiquitin-like modifier-activating enzyme 1

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    1 Details

  • Highest Development Stage:

    Phase 1 Clinical

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