CD58

CD58 Overview

English NameLymphocyte function-associated antigen 3Approved Drugs0
Drugs in Clinical Trials1Target SynonymCD58 Antigens,Surface glycoprotein LFA-3,LFA3,LFA-3,CD58 Molecule,CD58 Antigen,CD58,CD58 Antigen, (Lymphocyte Function-Associated Antigen 3)
Highest Development StageClinical
English NameLymphocyte function-associated antigen 3
Target SynonymCD58 Antigens,Surface glycoprotein LFA-3,LFA3,LFA-3,CD58 Molecule,CD58 Antigen,CD58,CD58 Antigen, (Lymphocyte Function-Associated Antigen 3)
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StageClinical

CD58 Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    His Tag (1)Fc Tag (1)

  • Conjugate

    Unconjugated (2)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
LF3-H5225
Human
HEK293
Human CD58 / LFA-3 Protein, His Tag
LF3-H5256
Human
HEK293
Human CD58 / LFA-3 Protein, Fc Tag
Total: 2
  • 1

CD58 Background

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

CD58 Synonyms

CD58,LFA3,Ag3

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Recombinant human LFA-3-antibody fusion protein (Taizhou Mabtech Pharmaceutical)ClinicalTaizhou Maibo Taike Biotechnology Co LtdPsoriasis
Details
  • Overview
  • Product List
  • Clinical Drug Information
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