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Home PageAll MoleculesCD8 alpha & beta
CD8 alpha & beta
CD8 alpha & beta Overview
| English Name | T-cell surface glycoprotein CD8 beta chain | Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 | Target Synonym | CD8b，CD8b Molecule |
| Highest Development Stage | Preclinical | ||
| English Name | T-cell surface glycoprotein CD8 beta chain |
| Target Synonym | CD8b，CD8b Molecule |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 |
| Highest Development Stage | Preclinical |
CD8 alpha & beta Product List
- Product Category
Protein (7)
- Product Status
Launched (7)
- Species
Human (4)Cynomolgus (2)Mouse (1)
- Tag
His Tag (4)His Tag & Avi Tag (2)Fc Tag (1)
- Conjugate
FITC Labeled (1)Unconjugated (4)Biotin-labeled (2)
Total: 7
- 1
CD8 alpha & beta Background
The CD8αβ heterodimer is a key cell surface co-receptor on cytotoxic T lymphocytes. It binds to MHC class I molecules on antigen-presenting cells, stabilizing the interaction between the T-cell receptor (TCR) and the peptide-MHC complex. This binding is essential for T-cell activation, positive selection in the thymus, and the effector function of mature CD8+ T cells. The β-chain (CD8β) modulates the affinity of the interaction, contributes to signal transduction, and promotes the stable surface expression of the heterodimer.
CD8 alpha & beta Synonyms
CD8 alpha & beta,CD8A & CD8B
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