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Home PageAll MoleculesCD8 alpha & beta
CD8 alpha & beta
CD8 alpha & beta Overview
| English Name | T-cell surface glycoprotein CD8 beta chain | Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 | Target Synonym | CD8b，CD8b Molecule |
| Highest Development Stage | Preclinical | ||
| English Name | T-cell surface glycoprotein CD8 beta chain |
| Target Synonym | CD8b，CD8b Molecule |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 0 |
| Highest Development Stage | Preclinical |
CD8 alpha & beta Product List
- Product Category
Protein (7)
- Product Status
Launched (7)
- Species
Human (4)Cynomolgus (2)Mouse (1)
- Tag
His Tag (4)His Tag & Avi Tag (2)Fc Tag (1)
- Conjugate
FITC Labeled (1)Unconjugated (4)Biotin-labeled (2)
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Total: 7
- 1
CD8 alpha & beta Background
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
CD8 alpha & beta Synonyms
CD8 alpha & beta,CD8A & CD8B
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