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Home PageAll MoleculesIL-12 R beta 1
IL-12 R beta 1
IL-12 R beta 1 Overview
| English Name | Interleukin-12 receptor | Approved Drugs | 0 |
| Drugs in Clinical Trials | 9 | Target Synonym | Receptors， Interleukin-12 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Interleukin-12 receptor |
| Target Synonym | Receptors， Interleukin-12 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 9 |
| Highest Development Stage | Phase 2 Clinical |
IL-12 R beta 1 Product List
- Product Category
Protein (7)
- Product Status
Launched (7)
- Species
Human (4)Cynomolgus (2)Mouse (1)
- Tag
His Tag (1)Fc Tag & Avi Tag (1)Fc Tag (2)His Tag & Avi Tag (3)
- Conjugate
Unconjugated (3)Biotin-labeled (4)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT ILB-H5255 |  Human | HEK293 | Human IL-12 R beta 1 / CD212 Protein, Fc Tag (MALS verified) |  |  |  |  Add to Cart |
HOT ILB-H52E1 | Human | HEK293 | Biotinylated Human IL-12 R beta 1 / CD212 Protein, His,Avitag™ (MALS verified) |  | | | Add to Cart |
HOT ILB-H52H9 | Human | HEK293 | Human IL-12 R beta 1 / CD212 Protein, His Tag (MALS verified) |  | | | Add to Cart |
HOT ILB-H82F7 | Human | HEK293 | Biotinylated Human IL-12 R beta 1 / CD212 Protein, Fc,Avitag™ |  | | | Add to Cart |
ILB-M52E1 |  Mouse | HEK293 | Biotinylated Mouse IL-12 R beta 1 / CD212 Protein, His,Avitag™ |  | | | Add to Cart |
ILB-C5253 |  Cynomolgus | HEK293 | Cynomolgus IL-12 R beta 1 Protein, Fc Tag |  | | | Add to Cart |
ILB-C52E2 | Cynomolgus | HEK293 | Biotinylated Cynomolgus IL-12 R beta 1 / CD212 Protein, His,Avitag™ |  | | | Add to Cart |
Total: 7
- 1
IL-12 R beta 1 Background
The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
IL-12 R beta 1 Synonyms
IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| KLT-1101 | KLT-1101 | Phase 2 Clinical | Kang Litai Pharmaceutical Co Ltd | Leukopenia; Melanoma; Sarcoma, Kaposi; Solid tumours; Thrombocytopenia | Details |
| Edodekin alfa | RO 247472; YM 01C | Phase 2 Clinical | F. Hoffmann-La Roche Ltd, Valeant, Wistar Institute | Abdominal Neoplasms; Asthma; Bacterial Infections; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Graft vs Host Disease; Hepatitis B; Hepatitis C; HIV Infections; Leishmaniasis; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Malaria; Melanoma; Neoplasms; Sarcoma, Kaposi; Solid tumours; Squamous Cell Carcinoma of Head and Neck | Details |
| RTX-224 | RTX-224 | Phase 2 Clinical | Rubius Therapeutics Inc | Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms | Details |
| KB-707 | KB707; KB-707 | Phase 2 Clinical | Krystal Biotech Inc | Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Melanoma; Neoplasms; Skin Melanoma; Solid tumours | Details |
| ASP-9801 | ASP-9801 | Phase 1 Clinical | Astellas Pharma Inc | Neoplasm Metastasis; Neoplasms; Solid tumours | Details |
| Tolododekin Alfa | ANK101; ANK-101 | Phase 1 Clinical | Ankyra Therapeutics Inc | Carcinoma, Basosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Rejection of renal transplantation; Skin Neoplasms; Soft Tissue Injuries; Solid tumours | Details |
| CLN-617 | CLN-617 | Phase 1 Clinical | Cullinan Therapeutics Inc | Solid tumours | Details |
| SON-1010 | SON-1010 | Phase 1 Clinical | Sonnet Biotherapeutics Inc | Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Sarcoma; Solid tumours | Details |
| phIL12 GET | Phase 1 Clinical | Institute Of Oncology Ljubljana | Carcinoma, Basal Cell | Details |
Product Reviews
K***n2024-10-05
0People LikeI’ve been using the IL12 receptor protein from Acro Biosystem in my antibody discovery research, and I’m highly satisfied with its quality. The protein exhibits excellent stability and bioactivity, which has been crucial in my experiments targeting immune responses. It’s been a reliable reagent, showing consistent results across various assays. I highly recommend this product for anyone involved in immunological research, particularly in therapeutic antibody development.
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