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Home PageAll MoleculesIL-31 RA
IL-31 RA
IL-31 RA Overview
| English Name | Interleukin-31 receptor subunit alpha | Approved Drugs | 1 |
| Drugs in Clinical Trials | 0 | Target Synonym | GLM-R，CRL，IL-31R subunit alpha，IL-31 receptor subunit alpha，Cytokine receptor-like 3，Gp130-like monocyte receptor，IL-31RA，ZcytoR17，IL-31R-alpha，PRO21384，GPL，CRL3，GLMR，Interleukin 31 Receptor A，Soluble Type I Cytokine Receptor CRL3，PLCA2，Class I Cytokine Receptor，hGLM-R，Gp130-like receptor |
| Highest Development Stage | Approved | ||
| English Name | Interleukin-31 receptor subunit alpha |
| Target Synonym | GLM-R，CRL，IL-31R subunit alpha，IL-31 receptor subunit alpha，Cytokine receptor-like 3，Gp130-like monocyte receptor，IL-31RA，ZcytoR17，IL-31R-alpha，PRO21384，GPL，CRL3，GLMR，Interleukin 31 Receptor A，Soluble Type I Cytokine Receptor CRL3，PLCA2，Class I Cytokine Receptor，hGLM-R，Gp130-like receptor |
| Approved Drugs | 1 |
| Drugs in Clinical Trials | 0 |
| Highest Development Stage | Approved |
IL-31 RA Product List
- Product Category
Protein (6)
- Product Status
Launched (6)
- Species
Human (4)Cynomolgus (1)Mouse (1)
- Tag
Fc Tag (3)His Tag (1)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)
- Conjugate
Unconjugated (4)Biotin-labeled (2)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT ILA-H52H7 |  Human | HEK293 | Human IL-31 RA Protein, His Tag, low endotoxin (MALS & SPR verified) |  |  |  |  Add to Cart |
HOT ILA-H82E9 | Human | HEK293 | Biotinylated Human IL-31 RA Protein, His,Avitag™ |  | | | Add to Cart |
HOT ILA-M5254 |  Mouse | HEK293 | Mouse IL-31 RA Protein, Fc Tag |  | |  | Add to Cart |
HOT ILA-H525b |  Cynomolgus | HEK293 | Cynomolgus IL-31 RA Protein, Fc Tag |  | | | Add to Cart |
ILA-H5256 | Human | HEK293 | Human IL-31 RA Protein, Fc Tag |  | | | Add to Cart |
ILA-H82F6 | Human | HEK293 | Biotinylated Human IL-31 RA Protein, Fc,Avitag™ |  | | | Add to Cart |
Total: 6
- 1
IL-31 RA Background
Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.
IL-31 RA Synonyms
IL-31 RA,IL-31RA,hGLM-R,CRL3,GPL,ZcytoR17,GLM-R,IL-31R-alpha,Gp130-like receptor
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Nemolizumab | CD-14152; CIM-331; M 5250; M 5250B | Approved | Chugai Pharmaceutical Co Ltd | Mitchga, Nemluvio | Japan | Dermatitis, Atopic; Pruritus | Maruho Co Ltd | 2022-03-28 | Dermatitis, Atopic; Prurigo; Prurigo Nodularis; Pruritus; Scleroderma, Systemic | Details |
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