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PADI2

PADI2 Product List

  • Product Category

    Protein (3)

  • Product Status

    Launched (3)

  • Species

    Human (1)Mouse (1)Cynomolgus (1)

  • Tag

    His Tag (3)

  • Conjugate

    Unconjugated (3)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
HOT
PA2-C5545
Cynomolgus
InsectCells
Cynomolgus PADI2 Protein, His Tag (MALS verified)
PA2-H5543
Human
InsectCells
Human PADI2 Protein, His Tag, low Endotoxin (InsectCells) (active enzyme)
PA2-M5544
Mouse
InsectCells
Mouse PADI2 Protein, His Tag (MALS verified)
Total: 3
  • 1

PADI2 Background

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
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