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Menu
Home PageAll MoleculesProlactin R
Prolactin R
Prolactin R Overview
| English Name | Prolactin receptor | Approved Drugs | 0 |
| Drugs in Clinical Trials | 2 | Target Synonym | PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin |
| Highest Development Stage | Phase 3 Clinical | ||
| English Name | Prolactin receptor |
| Target Synonym | PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 2 |
| Highest Development Stage | Phase 3 Clinical |
Prolactin R Product List
- Product Category
Protein (7)
- Product Status
Launched (7)
- Species
Human (4)Cynomolgus (1)Rat (1)Mouse (1)
- Tag
Fc Tag (1)His Tag (5)His Tag & Avi Tag (1)
- Conjugate
Unconjugated (6)Biotin-labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human Prolactin R / PRLR Protein, Fc Tag |  |  |  |  Add to Cart | |
| Human | HEK293 | Human Prolactin R / PRLR Protein, His Tag&Tag Free, low endotoxin (MALS verified) | | | Add to Cart | ||
| Human | HEK293 | Human Prolactin R / PRLR Protein, His Tag |  | | | Add to Cart | |
| Human | HEK293 | Biotinylated Human Prolactin R / PRLR Protein, His,Avitag™ (MALS verified) |  | | | Add to Cart | |
 Mouse | HEK293 | Mouse Prolactin R / PRLR Protein, His Tag (MALS & SPR verified) |  | |  | Add to Cart | |
 Cynomolgus | HEK293 | Cynomolgus Prolactin R Protein, His Tag (MALS verified) |  | | | Add to Cart | |
 Rat | HEK293 | Rat Prolactin R / PRLR Protein, His Tag (MALS & SPR verified) |  | | | Add to Cart |
Total: 7
- 1
Prolactin R Background
As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
Prolactin R Synonyms
Prolactin R,PRLR,PRL-R
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| BAY-1158061 | BAY-1158061; HMI-115 | Phase 3 Clinical | Bayer AG | Alopecia; Endometriosis; Pain | Details |
| ABS-201 | ABS-201 | Phase 2 Clinical | Absci Corp | Alopecia; Skin Diseases | Details |
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