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UBE1

UBE1 Overview

English NameUbiquitin-like modifier-activating enzyme 1Approved Drugs0
Drugs in Clinical Trials1Target SynonymEC:6.2.1.45，UBE1，Ubiquitin-Activating Enzyme E1 (A1S9T And BN75 Temperature Sensitivity Complementing)，UBA1， Ubiquitin-Activating Enzyme E1 Homolog (Yeast)，POC20 Centriolar Protein Homolog (Chlamydomonas)，Ubiquitin-Like Modifier Activating Enzyme 1，Testicular Secretory Protein Li 63，EC 6.2.1.45，CFAP124，AMCX1，POC20，SMAX2，UBA1A，UBE1X，A1S9，A1ST，GXP1，Ubiquitin-activating enzyme E1，Protein A1S9，A1S9T，Ubiquitin-like modifier-activating enzyme 1，UBA1，Ubiquitin Like Modifier Activating Enzyme 1，A1S9T And BN75 Temperature Sensitivity Complementing，UBA1， Ubiquitin-Activating Enzyme E1 Homolog A，POC20 Centriolar Protein Homolog
Highest Development StagePhase 1 Clinical
English NameUbiquitin-like modifier-activating enzyme 1
Target SynonymEC:6.2.1.45，UBE1，Ubiquitin-Activating Enzyme E1 (A1S9T And BN75 Temperature Sensitivity Complementing)，UBA1， Ubiquitin-Activating Enzyme E1 Homolog (Yeast)，POC20 Centriolar Protein Homolog (Chlamydomonas)，Ubiquitin-Like Modifier Activating Enzyme 1，Testicular Secretory Protein Li 63，EC 6.2.1.45，CFAP124，AMCX1，POC20，SMAX2，UBA1A，UBE1X，A1S9，A1ST，GXP1，Ubiquitin-activating enzyme E1，Protein A1S9，A1S9T，Ubiquitin-like modifier-activating enzyme 1，UBA1，Ubiquitin Like Modifier Activating Enzyme 1，A1S9T And BN75 Temperature Sensitivity Complementing，UBA1， Ubiquitin-Activating Enzyme E1 Homolog A，POC20 Centriolar Protein Homolog
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 1 Clinical

UBE1 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
UB1-H5248
Human
InsectCells
Human UBE1 / UBA1 Protein, His Tag (MALS verified)
Total: 1
  • 1

UBE1 Background

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

UBE1 Synonyms

A1S9T and BN75 temperature sensitivity complementing,A1S9T,A1ST,AMCX1,GXP1,MGC4781,POC20 centriolar protein homolog,POC20,Protein A1S9,SMAX2,UBA1,UBA1, ubiquitin-activating enzyme E1 homolog A,UBA1A,UBE1,UBE1A1S9,UBE1X,ubiquitin-activating enzyme E1 (A1S9

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
TAK-243TAK-243; MLN-7243Phase 1 ClinicalTakeda Pharmaceutical Co LtdLeukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Solid tumours
Details
  • Overview
  • Product List
  • Clinical Drug Information
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