Integrin alpha V beta 6 Protein

Home
Products

Products by Category

Recombinant proteins and more
Multi-pass Transmembrane Proteins and Technology PlatformsNew FDA DMF Filed ProteinsHot SARS-CoV-2 Related ProductsHot Immune Checkpoint ProteinsHot Targets of CAR-T Cell TherapyNew CytokinesHot Biosimilar Drug TargetsHot Tumor MicroenvironmentHot Anti-idiotypic AntibodyHot Fc Receptor Proteins Llama IgG Fc Fusion ProteinNew Bio-Markers & CD Antigens ActiveMax -Best Cytokines Viral Proteins Enzymes Antibodies All Recombinant Proteins

Pre-labeled proteins
CAR rapid detection reagentsStar Staining Biotinylated protein collectionHot FITC & PE labeled ProteinsNew Fluorescent fusion proteins
Kits
SARS-CoV-2 Related Kit ProductsNew Pre-Coupling Magnetic BeadsNew ELISA Assay Kits for Quantitative Analysis of Therapeutic Antibodies in Serum Samples Inhibitor Screening Kits
Others
HPLC-verified Proteins Integrin - Integrin Proteins BCMA - B-Cell Maturation Antigen TIGIT - TIGIT Signaling Axis CD24 & Siglec-10 proteinsHot

Hot Products

Supports on COVID-19 R&D
Reagents for vaccine developmentNew Reagents for diagnostic developmentNew SARS-CoV-2 related productsNew SARS-CoV-2 related kitsNew SARS-CoV-2 mutant productsNew
Others
Multi-pass Transmembrane Proteins and Technology PlatformsNew Claudin18.2 ProteinsNew Bispecific antibody targetsHot Targets for ADCsHot IL-2 ReceptorsHot CD19 proteinsHot Anti-FMC63 mAbHot CD3 proteinsHot B7 family proteinsHot TNFSF proteinsHot VEGF proteinsHot CD39/CD73 proteinsNew Siglec-15 proteinsHot CD20 proteinsExclusive PD1 proteinsHot
Services

Innovation Lab
SPR /BLI analytical serviceNew Anti-Idiotypic AntibodyNew Enzyme-Linked Immunosorbent Assay (ELISA) Service New
Licensing Opportunities
Anti-TIM-3 monoclonal antibody New Anti-LAG-3 monoclonal antibody New Target 4-1BB monoclonal antibody New
Supports

How to Order Shipping & Payments Global Distributors Testimonials Download Brochures Download COA
Applications

The Process of How SARS-CoV-2 Infects the Host Quantitative Analysis of mAb in Serum Evaluation of CAR Expression
Company

About Us Join Us Contact Us
Activities

News Exhibitions Promotion
COVID-19 R&D ^New

Integrin alpha V beta 6

Brief Information

Name:Integrin alpha-V/beta-6
Target Synonym:

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 2 Clinical


IT6-H82E4	Human	Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free
IT6-H52E1	Human	Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free

Cat. No.

Species

Product Description

Structure

Purity

Feature

IT6-H82E4

Human

Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free

IT6-H52E1

Human

Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free

Part of Bioactivity data

IT6-H52E1-ELISA

Immobilized Human ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT6-H52E1) at 5 μg/mL (100 μL/well) can bind Biotinylated Human Latent TGF-Beta 1, His,Avitag (Cat. No. TG1-H82Qb) with a linear range of 0.5-4 ng/mL (QC tested).

Protocol

IT6-H82E4-ELISA

Biotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag FreeBiotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT6-H82E4) ELISA bioactivity

Immobilized Human TGFB1, His Tag (Cat. No. TG1-H524x) at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT6-H82E4) with a linear range of 2-10 ng/mL (QC tested).

Protocol

Synonym Name

Integrin alpha V beta 6,ITGAV&ITGB6,ITGAV&B6

Background

Integrin alpha V beta 6 is a heterodimer of beta-6 associating with alpha-V. Integrin alpha-V beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Also, Integrin alpha-V beta-6 acts as a receptor for coxsackievirus A9 and coxsackievirus B1 as well as herpes simplex virus-1/HHV-1. Furthermore, it binds the TGF-beta latency

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
[18F]FP-R01-MG	[18F]FP-R01-MG; [18F]FP-R01-MG-F2	Phase 1 Clinical	Pliant Therapeutics, Stanford University, Chinese Academy Of Medical Science & Peking Union Medical College	Idiopathic Pulmonary Fibrosis; Pancreatic Neoplasms	Details
IDL-2965	IDL-2965	Phase 2 Clinical	Indalo Therapeutics	Non-alcoholic Fatty Liver Disease; Idiopathic Pulmonary Fibrosis	Details
PLN-74809	PLN-74809	Phase 2 Clinical	Pliant Therapeutics	Idiopathic Pulmonary Fibrosis; Respiratory Distress Syndrome, Adult; Cholangitis, Sclerosing	Details