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Your Position: Home > Integrin alpha V beta 6

Integrin alpha V beta 6

Integrin alpha V beta 6 Molecule Information

Name:Integrin alpha-V/beta-6
Target Synonym:

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:Phase 2 Clinical

Integrin alpha V beta 6 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
IT6-H82E4	Human	Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free
IT6-H52E1	Human	Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free

Integrin alpha V beta 6 Part of Bioactivity data

IT6-H52E1-ELISA

Immobilized Human ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT6-H52E1) at 5 μg/mL (100 μL/well) can bind Biotinylated Human Latent TGF-Beta 1, His,Avitag (Cat. No. TG1-H82Qb) with a linear range of 0.5-4 ng/mL (QC tested).

Protocol

IT6-H82E4-ELISA

Biotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag FreeBiotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT6-H82E4) ELISA bioactivity

Immobilized Human TGFB1, His Tag (Cat. No. TG1-H524x) at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT6-H82E4) with a linear range of 2-10 ng/mL (QC tested).

Protocol

Integrin alpha V beta 6 Molecule Synonym Name

Integrin alpha V beta 6,ITGAV&ITGB6,ITGAV&B6

Integrin alpha V beta 6 Molecule Background

Integrin alpha V beta 6 is a heterodimer of beta-6 associating with alpha-V. Integrin alpha-V beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Also, Integrin alpha-V beta-6 acts as a receptor for coxsackievirus A9 and coxsackievirus B1 as well as herpes simplex virus-1/HHV-1. Furthermore, it binds the TGF-beta latency

Integrin alpha V beta 6 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
[18F]FP-R01-MG	[18F]FP-R01-MG; [18F]FP-R01-MG-F2	Phase 1 Clinical	Pliant Therapeutics, Stanford University, Chinese Academy Of Medical Science & Peking Union Medical College	Idiopathic Pulmonary Fibrosis; Pancreatic Neoplasms	Details
IDL-2965	IDL-2965	Phase 2 Clinical	Indalo Therapeutics	Non-alcoholic Fatty Liver Disease; Idiopathic Pulmonary Fibrosis	Details
PLN-74809	PLN-74809	Phase 2 Clinical	Pliant Therapeutics	Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Cholangitis, Sclerosing	Details