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Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (MALS verified)

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Cat. No. / Size
Price
Qty
CC8-MY2406-20ug
$168.00
CC8-MY2406-100ug
$505.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Source

    Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) is a mouse monoclonal antibody recombinantly expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    11C4C1

  • Isotype

    Mouse IgG2a, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    mRNA-CCR8

  • Specificity

    Specifically recognizes Human CCR8 Protein.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 12 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     CCR8 ELISA

    Immobilized Human CCR8 Protein (VLP) (Cat. No. CC8-H52P5) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) with a linear range of 0.08-3 ng/mL. Virus-Like Particle (VLP) Protein Isotype Control (Cat. No. VLP-N5213) is verified not recoginized by Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) in low concentration (QC tested).

    Protocol
  • Bioactivity-FACS

     CCR8 FACS

    1e6 of HEK293/Human CCR8 Stable Cells Line were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) and isotype control antibody respectively, washed and then followed by PE anti-mouse IgG2a antibody and analyzed with FACS (QC tested).​

    Protocol
  •  CCR8 FACS

    1e6 of HEK293/Human CCR8 Stable Cells Line (Cat. No. CHEK-ATP140) were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) and isotype control antibody (Cat. No. DNP-M487) respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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Background

CCR8 is a G protein-coupled chemokine receptor expressed on regulatory T cells and in tumor microenvironments, mediating chemotaxis, immune regulation, and pathological processes like inflammation or cancer progression. The unconjugated anti-human CCR8 antibody enables specific detection of human CCR8.

Recent Advances

 
Drug Development Progress
  • English Name:

    C-C chemokine receptor type 8

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    20 Details

  • Highest Development Stage:

    Phase 3 Clinical

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