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PE-Labeled Monoclonal Anti-Human CD197 / CCR7 Antibody, Mouse IgG2a (AS651) (0.03% Proclin)

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Cat. No. / Size
Price
Qty
FABm057-01-100tests (50tests X 2)
$210.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Source

    Monoclonal Anti-Human CD197 / CCR7 Antibody, Mouse IgG2a (AS651) is a recombinant mouse monoclonal antibody expressed in HEK293 cells, providing improved batch-to-batch consistency and long-term supply security.

  • Clone

    AS651

  • Isotype

    Mouse IgG2a, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    Purified Human CD197 / CCR7 Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Specificity

    This antibody specifically recognizes human CD197 / CCR7 protein.

  • Application

    Flow Cytometry (Evaluation of the expression of CD197 / CCR7 on Human cells).

  • Recommended Dilution

    1:20

  • Isotype Control

    The isotype control is sold separately; please refer to Cat. No. DNP-PM487 for product information.

  • Form

    Liquid

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    Liquid product is shipped at blue ice.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-FACS

     CD197 FACS

    Flow cytometric analysis of CCR7-HEK293T cells stained with PE-Labeled Monoclonal Anti-Human CD197 / CCR7 Antibody, Mouse IgG2a (AS651) (Cat. No. FABm057-01) at a 1:20 dilution. For the recommended staining condition, 5 μL of antibody stock solution is used to stain 1e6 cells in a final volume of 100 μL. An isotype control antibody was used as a negative control. PE fluorescence signal was measured to evaluate the binding activity of the antibody (QC tested).

    Protocol

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Background

The anti-Human CD197 (CCR7) monoclonal antibody specifically binds to cell-surface CCR7 (CD197), a seven-transmembrane G-protein-coupled receptor that interacts with chemokines CCL19 and CCL21. CCR7 mediates leukocyte homing to secondary lymphoid tissues, and its differential expression distinguishes T cell subsets. Aberrant CCR7 expression is linked to lymphoma metastasis and autoimmune disease progression, making it a key target for immunotherapy research. PE-labeled CCR7 antibody can facilitate relevant drug research and development.

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