Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (MALS verified)

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Cat. No. / Size
Price
Qty
NEE-MY2392-100ug
$350.00
NEE-MY2392-1mg (250ug X 4)
$2310.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) is a chimeric monoclonal antibody recombinantly expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    8B5

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein is expressed from human 293 cells

  • Specificity

    Specifically recognizes Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein; Has cross-reactivity in ELISA with: Influenza A [Darwin/6/2021] Neuraminidase NA(H3N2) Protein, Influenza A virus (A/Thailand/8/2022) NA(H3N2) Protein, Influenza A virus (A/Croatia/10136RV/2023) & (A/District of Columbia/27/2023) NA(H3N2) Protein, Influenza A virus (A/Massachusetts/18/2022) NA(H3N2) Protein.

  • Cross Verification

    This product No cross-reactivity in ELISA with
    Influenza B [PHUKET/3073/2013] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5246).
    Influenza B [Austria/1359417/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5245).
    Influenza A [Sydney/5/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5248).
    Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. HA1-V5245).
    Influenza A [Guangdong/18SF020(H5N6)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524h).
    Influenza A [turkey/Germany-MV/R2472/2014(H5N8)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5249).
    Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524k).
    Influenza A [Victoria/2570/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524e).
    Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524m).

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Neuraminidase/NA (Influenza Virus) ELISA

    Immobilized Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein, His Tag (Cat. No. NE2-V5249) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (Cat. No. NEE-MY2392) with a linear range of 0.06-2 ng/mL (QC tested).

    Protocol
  •  Neuraminidase/NA (Influenza Virus) ELISA

    Immobilized Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5247) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (Cat. No. NEE-MY2392) with a linear range of 0.05-2 ng/mL (Routinely tested).

    Protocol

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Background

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

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