PE-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag (Site-specific conjugation)

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Cat. No. / Size
Price
Qty
ILP-HP2H3-25tests
$345.00
ILP-HP2H3-200tests
$2245.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    IL1RAP, IL-1RAcP, C3orf13, IL1R3

  • Source

    PE-Labeled Human IL-1 RAcP / IL-1 R3, His Tag (ILP-HP2H3) is produced via site-specific conjugation of PE to Human IL-1 RAcP / IL-1 R3 Protein, His Tag under optimal conditions with a proprietary technology. PE-Labeled Human IL-1 RAcP, His Tag (ILP-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3-1).

    Predicted N-terminus: Ser 21

    Request for sequence

  • Molecular Characterization

    IL-1 RAcP Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 42.7 kDa.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Application

    Please note that this product is NOT compatible to streptavidin detection system.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 0.5%BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Background

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Recent Advances

 
Drug Development Progress
  • English Name:

    Interleukin-1 receptor accessory protein

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    8 Details

  • Highest Development Stage:

    Phase 2 Clinical

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