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Your Position: Home > FGF19

FGF19

Brief Information

Name:Fibroblast growth factor 19
Target Synonym:FGF-19
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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Cat. No. Species Product Description Structure Purity Feature
FG9-H51H3 Human Human FGF19 Protein, His Tag
FG9-H51H3-structure
FG9-H51H3-sds
FG9-H5253 Human Human FGF19 Protein, Fc Tag
FG9-H5253-structure
FG9-H5253-sds

Part of Bioactivity data

FG9-H5253-SPR
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human FGF19, Fc Tag (Cat. No. FG9-H5253) on Protein A Biosensor, can bind Human FGF R4, His Tag (Cat. No. FG4-H5228) with an affinity constant of 1 μM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

Synonym Name

FGF19/FGF-19/Fibroblast growth factor 19

Background

Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR  was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

Clinical and Translational Updates

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